Thermo Fisher Scientific CD226 (DNAM-1) Chimeric Recombinant Rabbit Monoclonal Antibody (10E5)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Flow Cytometry (Flow)

1:100

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

10E5

Immunogen

This antibody was raised by immunising Lewis and Lou/M rats with the murine Th1 cell clone AE7 and Th1 cell lines derived from 5B6 and DO11.10 TCR transgenic mice. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD226 (DNAM-1),uniProtId:Q8K4F0-1,ncbiNodeId:10090,antigenRange:1-333,antigenLength:333,antigenImageFileName:MA5-48218_CD226_DNAM-1_Q8K4F0-1_Rabbit.svg,antigenImageFileNamePDP:MA5-48218_CD226_DNAM-1_Q8K4F0-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3074661

Product Specific Information

Specificity: This antibody is specific for murine CD226.

Preparation: This antibody was raised by immunising Lewis and Lou/M rats with the murine Th1 cell clone AE7 and Th1 cell lines derived from 5B6 and DO11.10 TCR transgenic mice, before screening for reactivity with Th1 clones and a lack of reactivity to Th2/Th0 cell lines.

Target Information

DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.