Thermo Fisher Scientific TAB1 Polyclonal Antibody
TAB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunoprecipitation에 최적화된 연구용 항체로, Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 435 and 485 of Human TAK1-binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1) regulates MAP3K7/TAK1-mediated signaling pathways, including those induced by TGF beta, interleukin 1, and WNT-1. TAB1 activates TAK1 kinase through interaction with its C-terminal portion, while the N-terminal region may inhibit TGF beta signaling. It can also activate MAPK14/p38α, providing an alternative activation pathway contributing to MAPK14 responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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