Thermo Fisher Scientific MAD3 Recombinant Rabbit Monoclonal Antibody (ARC2333)
Recombinant rabbit monoclonal antibody targeting human MAD3/MXD3. Validated for WB and ELISA. High specificity and affinity purified. Supplied in liquid form with stabilizing buffer for reliable research performance.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2333 |
| Immunogen | Recombinant fusion protein containing amino acids 100–190 of human MAD3/MXD3 (Q9BW11) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897929 |
Product Specific Information
- Positive Samples: A-549, DU145, Jurkat
- Immunogen Sequence:
RRARMHIQKL EDQEQRARQL KERLRSKQQS LQRQLEQLRG LAGAAERERL RADSLDSSGL SSERSDSDQE ELEVDVESLV FGGEAELLRG F
Target Information
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX, which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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