Thermo Fisher Scientific BCL2L12 Recombinant Rabbit Monoclonal Antibody (ARC2334)
BCL2L12 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ELISA, IP에 사용 가능. 인간 시료 반응성. HEK293 세포에서 발현된 재조합 항체이며, 비결합형 액상 형태로 제공. 항세포자멸 억제 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2334 |
| Immunogen | Recombinant fusion protein corresponding to amino acids 200–300 of human BCL2L12 (Q9HB09) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897930 |
Product Specific Information
- Positive Samples: MCF7, PC-3
- Immunogen sequence:
GPPSTEKEAI LRRLVALLEE EAEVINQKLA SDPALRSKLV RLSSDSFARL VELFCSRDDS SRPSRACPGP PPPSPEPLAR LALAMELSRR VAGLGGTLAG L
Target Information
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2).
The encoded protein is an anti-apoptotic factor that inhibits caspases 3 and 7 in the cytoplasm.
In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes.
Overexpression of this gene has been detected in various cancers.
A pseudogene exists on chromosome 3, and alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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