Thermo Fisher Scientific Phospho-C/EBP alpha (Thr226) Polyclonal Antibody
C/EBPα 단백질의 Thr226 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 1 mg/mL 액상 형태로 제공. -20°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human C/EBP-alpha around the phosphorylation site of Thr226 (H-P-TP-P-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555030 |
Target Information
The C/EBP (CCAAT/enhancer binding protein) family of transcription factors—alpha, beta, delta, and epsilon—are widely expressed proteins found in various tissues. These domains contain an evolutionarily conserved five-amino acid motif (regulatory domain motif, RDM) that conforms to the consensus sequence (I/V/L)KXEP.
One of the major roles of these transcription factors is metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in adipose cell development.
Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display distinct roles in gene regulation.
From a neurological perspective, C/EBPs have been implicated in mediating nerve growth factor, altering synaptic plasticity, and influencing inflammatory response in Alzheimer’s disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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