Thermo Fisher Scientific GRK7 Polyclonal Antibody
GRK7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC(Paraffin) 분석에 적합합니다. Retina 특이적 GRK7 단백질 연구용으로 사용되며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA514807
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 508–538 amino acids from the C-terminal region of human GRK7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2115478 |
Target Information
GRK7 is a serine/threonine kinase specifically expressed in the retina. It phosphorylates cone opsins and initiates their deactivation.
Protein kinases transfer a phosphate group from ATP to substrate proteins, mediating signal transduction and regulating cellular processes such as metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products and is classified into 8 major groups based on catalytic domain sequences.
Tyrosine kinase (TK) groups regulate cell-cell interactions, including differentiation, adhesion, motility, and death. There are about 90 TK genes, including receptor TKs (EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and cytosolic TKs (ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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