Thermo Fisher Scientific Phospho-PTPRA (Ser180) Polyclonal Antibody
Phospho-PTPRA (Ser180) 폴리클로날 항체로, 인산화된 PTPRA 단백질 검출에 적합합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Rabbit IgG 기반으로 제작되었습니다. Protein A 정제 및 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human PTPRA around the phosphorylation site of Ser180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Phosphorylation of receptors by protein kinases is a reversible process regulated by protein phosphatases. The balance between kinase and phosphatase activity allows cells to dynamically switch between phosphorylated and dephosphorylated states in response to environmental stimuli. Dysregulation of this balance can contribute to uncontrolled cell growth, cancer, and developmental disorders. Protein phosphatases can be regulated through expression levels, subcellular localization, phosphorylation of subunits, and endogenous inhibitors, influencing multiple signaling pathways and physiological responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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