Thermo Fisher Scientific TMED2 Polyclonal Antibody
TMED2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, IP 등 다양한 응용에 사용 가능. 고순도 항원 친화 크로마토그래피 정제. 인간 시료 반응성, 액상 형태로 안정적인 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human TMED2 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902908 |
Target Information
TMED2 is a protein coding gene involved in vesicular protein trafficking. It mainly functions in the early secretory pathway and post-Golgi membranes. TMED2 acts as a cargo receptor for incorporating secretory molecules into transport vesicles and contributes to vesicle coat formation. In COPII vesicle-mediated transport, it is involved in the movement of GPI-anchored proteins and interacts with TMED10, SEC24C, and SEC24D. It also plays a role in COPI vesicle-mediated retrograde transport by regulating ARFGAP1 activity, ensuring proper cargo selection. TMED2 is associated with trafficking of GPCRs such as F2RL1, OPRM1, and P2RY4, and facilitates CASR maturation and Golgi apparatus organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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