Thermo Fisher Scientific PRDX3 Polyclonal Antibody
PRDX3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합하며, 인간 시료 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5144908
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 165–200. Recombinant protein control fragment (Product #RP-109866). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092344 |
Product Specific Information
- Immunogen sequence: TKQISRDYGV LLEGSGLALR GLFIIDPNGV IKHLSV
- Antigen sequence identity: Mouse 89%; Rat 92%
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are known to be involved in cell proliferation, differentiation, and apoptosis. Many isoforms (approximately 50 proteins) share amino acid sequence homology and contain an active site cysteine residue with thiol-specific antioxidant activity.
Mammalian Prxs consist of six members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx types. Except Prx VI (1-Cys subgroup), the other five 2-Cys Prx isotypes have thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system.
Mammalian Prxs are 20–30 kDa in size and vary in subcellular localization: Prx I, II, and VI in cytosol; Prx III in mitochondria; Prx IV in ER and secretion; Prx V in peroxisome, mitochondria, and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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