Thermo Fisher Scientific CENPF Polyclonal Antibody
Thermo Fisher Scientific의 CENPF Polyclonal Antibody는 인간 시료에 반응하는 토끼 IgG 항체로, ICC/IF 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태, 장기 보관 시 -20°C 유지 권장. 세포분열 관련 단백질 연구용으로 사용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 620–761. Recombinant protein control fragment (Product #RP-110098). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3092014 |
Product Specific Information
- Immunogen sequence:
SCWKSENEKL LTQMESEKEN LQSKINHLET CLKTQQIKSH EYNERVRTLE MDRENLSVEI RNLHNVLDSK SVEVETQKLA YMELQQKAEF SDQKHQKEIE NMCLKTSQLT GQVEDLEHKL QLLSNEIMDK DRCYQDLHAE YE - Antigen sequence identity: Mouse 69%; Rat 73%
Target Information
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase.
In late G2, it associates with the kinetochore and maintains this association through early anaphase.
It localizes to the spindle midzone and intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded.
The localization suggests a role in chromosome segregation during mitosis.
It may form either a homodimer or heterodimer.
Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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