Thermo Fisher Scientific CENPF Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 620-761. Recombinant protein control fragment (Product #RP-110098). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CENPF,uniProtId:P49454-1,ncbiNodeId:9606,antigenRange:620-761,antigenLength:3114,antigenImageFileName:PA5-144905_CENPF_P49454-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144905_CENPF_P49454-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3092014

Product Specific Information

Immunogen sequence: SCWKSENEKL LTQMESEKEN LQSKINHLET CLKTQQIKSH EYNERVRTLE MDRENLSVEI RNLHNVLDSK SVEVETQKLA YMELQQKAEF SDQKHQKEIE NMCLKTSQLT GQVEDLEHKL QLLSNEIMDK DRCYQDLHAE YE

Antigen sequence identity: Mouse 69%; Rat 73%

Target Information

This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitosis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.