Thermo Fisher Scientific GluR4 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human GluR4. Validated for ICC/IF applications. Supplied as a liquid, unconjugated form with 0.3 mg/mL concentration. Suitable for research on excitatory neurotransmission and glutamate receptor function.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 177–230). Recombinant protein control fragment: Product # RP-109960 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3092111 |
Product Specific Information
Immunogen sequence:
NGWHVSAICV ENFNDVSYRQ LLEELDRRQE KKFVIDCEIE RLQNILEQIV SVGK
Antigen sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors show slower kinetics and higher Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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