Thermo Fisher Scientific ZIP4 Polyclonal Antibody
SLC39A4(ZIP4) 단백질을 인식하는 Rabbit Polyclonal Antibody. WB 및 ICC/IF 실험에 적합하며, 인간 유래 시료에 반응. 1 mg/mL 농도의 액상 형태로 제공되며, PBS(glycerol 포함) 완충액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC39A4 (Accession Q6P5W5), corresponding to amino acid residues D433–N483 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851403 |
Product Specific Information
Antibody detects endogenous levels of total SLC39A4.
Target Information
The zinc transporter ZIP4 (SLC39A4) is a member of a family of divalent ion transporters. Zinc is an essential ion involved in cellular growth, development, and differentiation. ZIP4 was first identified as a zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in dietary zinc absorption. Aberrant expression of ZIP4 has been linked to cancer progression, including pancreatic and hepatocellular carcinomas, where it can repress apoptosis, enhance cell cycle progression, and increase migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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