Thermo Fisher Scientific PTGR2 Polyclonal Antibody
PTGR2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 Affinity chromatography 정제, PBS/glycerol buffer 저장. 인간 및 랫트 반응성.
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Thermo Fisher Scientific PTGR2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PTGR2 (Accession Q8N8N7), corresponding to amino acid residues I186–I236 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851404 |
Product Specific Information
This antibody detects endogenous levels of total ZADH1.
Target Information
ZADH1 (zinc binding alcohol dehydrogenase, domain containing 1), also known as PTGR2 (prostaglandin reductase 2), PGR2 or 15-oxoprostaglandin 13-reductase, is a 351 amino acid cytoplasmic protein belonging to the NADP-dependent oxidoreductase L4BD family.
Functioning as a 15-oxoprostaglandin 13-reductase, ZADH1 catalyzes the conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2 in a NADPH-dependent manner.
ZADH1 overexpression represses PPAR gamma transcriptional activity and adipocyte differentiation.
It is widely expressed, with highest levels in heart, kidney, liver, pancreas, and prostate, and moderate levels in brain, small intestine, lung, testis, and skeletal muscle.
ZADH1 exists as a monomer, utilizes NADPH as a cofactor, and undergoes alternative splicing to produce two isoforms encoded by a gene located on human chromosome 14q24.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-101972_PTGR2_Q8N8N7-1_Rabbit.svg, PA5-101972_PTGR2_Q8N8N7-1_Rabbit_PDP.jpeg)
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