Thermo Fisher Scientific Beclin 2 Polyclonal Antibody
Beclin 2 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. C-terminal synthetic peptide를 면역원으로 사용. 1 mg/mL 농도, -20°C 보관, 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the C-terminal of Mouse Beclin 2 (aa 410–421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735518 |
Product Specific Information
A 1:1,000 dilution of PA5-77777 was sufficient for detection of Beclin 2 in 15 µg of Human HeLa Cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 48 kDa.
Target Information
Beclin 2 is involved in two distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptor turnover. It regulates degradation in lysosomes of various G-protein coupled receptors via interaction with GPRASP1/GASP1. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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