Thermo Fisher Scientific CXCL13 Monoclonal Antibody (13)
개 전용 CXCL13 단클론 항체로 ELISA에 적합. 보존제가 없는 액상 형태이며 1 mg/mL 농도로 제공. 단백질 A로 정제되어 고순도 확보. 단기 4°C, 장기 -20°C 보관 권장. CXCL13의 면역학적 연구 및 바이오마커 분석에 활용 가능.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 13 |
| Immunogen | Recombinant Canine BCA-1/CXCL13 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2784912 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Canine BCA-1/CXCL13.
Target Information
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in secondary lymphoid organs. It promotes the migration of B lymphocytes (B-1 and B-2) to follicles of the spleen, lymph nodes, and Peyer’s patches.
Produced by macrophages, the highest constitutive producers in mice include large peritoneal macrophages, Kupffer cells, and lung macrophages (both CD11c+ and CD11c−).
The cellular ligand for CXCL13 is CXCR5 (also known as BLR-1), expressed on B cells, Tfh cells, and some memory T cells.
CXCL13 plays an important role in chronic lymphocytic leukemia (CCL) development and serves as a plasma biomarker for germinal center activity and the generation of broadly neutralizing antibodies against HIV.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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