Thermo Fisher Scientific ADAMTS4 Monoclonal Antibody (OTI2G8), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
• For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The ADAMTS4 gene encodes a member of the ADAMTS protein family, characterized by domains such as a propeptide region, metalloproteinase domain, disintegrin-like domain, and thrombospondin type 1 motif.
This enzyme lacks a C-terminal TS motif and is involved in the degradation of aggrecan (a major cartilage proteoglycan) and brevican (a brain-specific extracellular matrix protein).
These activities suggest roles in arthritic disease and central nervous system processes, including glioma progression.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.