Thermo Fisher Scientific PMM2 Polyclonal Antibody
PMM2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 적합. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, -20°C 보관. 세포질 내 PMM2 검출에 유용.
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Thermo Fisher Scientific PMM2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–246 of human PMM2 (NP_000294.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914452 |
Product Specific Information
Positive test controls include: HepG2, A-549, HeLa, 293T, NIH/3T3, Mouse liver, Mouse intestine, Rat brain.
The target is usually found in the following locations: Cytoplasm.
Immunogen sequence:
MAAPGPALCL FDVDGTLTAP RQKITKEMDD FLQKLRQKIK IGVVGGSDFE KVQEQLGNDV VEKYDYVFPE NGLVAYKDGK LLCRQNIQSH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVAD LRKEFAGKGL TFSIGGQISF DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDHEI FTDPRTMGYS VTAPEDTRRI CELLFS
Target Information
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides.
Mutations in this gene can cause defects in glycoprotein biosynthesis, manifesting as carbohydrate-deficient glycoprotein syndrome type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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