Thermo Fisher Scientific IL-16 Polyclonal Antibody
IL-16 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등에 사용 가능. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 4°C 또는 -20°C에서 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IL16. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M tris glycine, pH 7, with 0.1M glycine, 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735954 |
Product Specific Information
- Positive Control: A549, Jurkat, NT2D1
- Predicted Reactivity: Chimpanzee (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, modulator of T cell activation, and inhibitor of HIV replication.
Its signaling is mediated by CD4 and involves proteolytic processing yielding two functional proteins.
The cytokine function is attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.
Caspase 3 is involved in proteolytic processing, and alternate splicing results in multiple transcript variants.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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