Thermo Fisher Scientific STAT5B Monoclonal Antibody (STAT5B/2657)
STAT5B 단백질을 인식하는 Mouse monoclonal 항체로, ELISA 및 Peptide Array에 사용 가능. Human 시료 반응성. Protein A/G 정제, 보존제 없음. -20°C 보관, 연구용 전용.
- 카탈로그번호
- 6777-MSM2-P1ABX
- 판매단위
- pk
카탈로그
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Applications
ELISA (ELISA)
- Tested Dilution: 1–5 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | STAT5B/2657 |
| Immunogen | Recombinant full-length human STAT5B protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and then form homo- or heterodimers that translocate to the cell nucleus, where they act as transcription activators. This protein mediates signal transduction triggered by various ligands such as IL2, IL4, CSF1, and different growth hormones. It is involved in biological processes including TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The gene has been found to fuse with the retinoic acid receptor-alpha (RARA) gene in a subset of acute promyelocytic leukemias (APLL). Dysregulation of this protein’s signaling pathways may contribute to APLL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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