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Thermo Fisher Scientific Notch-1 Monoclonal Antibody (mN1A)
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Thermo Fisher Scientific Notch-1 Monoclonal Antibody (mN1A)

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Notch-1 단백질을 인식하는 단클론 항체로 Western blot 및 IHC(P) 적용 가능. 인간, 생쥐, 랫트 반응성. 단백질 A로 정제된 액상 형태. 세포막과 핵에서 발현되는 Notch-1 검출에 적합.

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pk
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Thermo Fisher Scientific 606-100 Notch-1 Monoclonal Antibody (mN1A) 100 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific Notch-1 Monoclonal Antibody (mN1A)

Thermo Fisher Scientific Notch-1 Monoclonal Antibody (mN1A)

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 2–10 µg/mL

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone mN1A
Immunogen A synthetic peptide of Notch-1
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Protein A
Storage Buffer PBS with proprietary stabilizer
Contains 0.01% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Positive control: Brain tissue
  • Cellular location: Cell membrane and nucleus

Target Information

The Notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in their extracellular region. Four Notch genes (Notch1, Notch2, Notch3, Notch4/Int-3) have been identified in mammals and are involved in the differentiation of the nervous system and other tissues.
The EGF-like proteins Delta and Serrate serve as ligands for Notch1.
Mature Notch proteins are heterodimeric receptors, formed by cleavage of Notch pre-proteins into an extracellular subunit (NEC) and a transmembrane subunit (Ntm) containing the intracellular region.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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