Thermo Fisher Scientific PSMB10 Recombinant Rabbit Monoclonal Antibody (3J3G5)
PSMB10 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot과 ELISA에 적합하며, 인간, 마우스, 랫트 시료에 반응. Protein A로 정제된 액상 항체로, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3J3G5 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–273 of human PSMB10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MLKPALEPRG GFSFENCQRN ASLERVLPGL KVPHARKTGT TIAGLVFQDG VILGADTRAT NDSVVADKSC EKIHFIAPKI YCCGAGVAAD AEMTTRMVAS KMELHALSTG REPRVATVTR ILRQTLFRYQ GHVGASLIVG GVDLTGPQLY GVHPHGSYSR LPFTALGSGQ DAALAVLEDR FQPNMTLEAA QGLLVEAVTA GILGDLGSGG NVDACVITKT GAKLLRTLSS PTEPVKRSGR YHFVPGTTAV LTQTVKPLTL ELVEETVQAM EVE
Target Information
The 20S proteasome is a protease complex responsible for cytosolic protein degradation and generation of peptide ligands for MHC class I molecules. Upon IFN-gamma stimulation, constitutive subunits LMP2, LMP7, and MECL-1 (LMP10) are replaced to form immunoproteasomes, which enhance class I antigen processing. Different combinations of these subunits can produce up to 36 proteasome subsets with distinct cleavage specificities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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