Thermo Fisher Scientific TRUB1 Recombinant Rabbit Monoclonal Antibody (2V8B9)
TRUB1 단백질을 인식하는 재조합 토끼 단일클론 항체로, IHC, ELISA, Peptide Array 등에 사용 가능. 높은 특이성과 재현성을 제공하며, HEK293 발현 시스템에서 생산됨. 단백질 A로 정제된 액상 항체로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
| Peptide Array | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2V8B9 |
| Immunogen | Chemical compounds corresponding to Pseudouridine 5-ribosyluracil Y |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
Pseudouridine is an isomer of the nucleoside uridine in which the uracil is attached via a carbon–carbon instead of a nitrogen–carbon glycosidic bond. It is the most abundant RNA modification in cellular RNA (PMID: 29104216).
After transcription and synthesis, RNA can be modified with over 100 chemically distinct modifications, which may regulate RNA expression post-transcriptionally. These modifications play roles in translation, localization, and stabilization of RNA.
Pseudouridine in rRNA and tRNA fine-tunes and stabilizes regional structures, maintaining functions in mRNA decoding, ribosome assembly, processing, and translation (PMID: 10902565, 23391857, 28045575).
Pseudouridine in snRNA enhances spliceosomal RNA–pre-mRNA interaction to facilitate splicing regulation (PMID: 27268497).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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