Thermo Fisher Scientific ATG4D Polyclonal Antibody
ATG4D 단백질(인간, 마우스, 랫트)에 반응하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to amino acids 123–474 of Human ATG4D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720009 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid cytoplasmic protein belonging to the C-54 family of cysteine proteases. It is predominantly expressed in skeletal muscle and testis. Atg4D functions as a cysteine protease required for autophagy, specifically cleaving the C-terminal region of target proteins to enable binding to autophagosomes. Its enzymatic activity is inhibited by N-ethylmaleimide, a thiol-reactive compound that modifies cysteine residues in proteins and peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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