
Thermo Fisher Scientific Taok2 Polyclonal Antibody
TAOK2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 생쥐 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C 또는 -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA529248
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Taok2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 3–285 of Human TAOK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546724 |
Product Specific Information
- Recommended positive control: Mouse brain
- Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (95%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TAOK2 (TAO1) is a serine/threonine kinase that may regulate the stress-responsive p38 MAP kinase pathway. In vitro, TAO2 activates MEK3, MEK4, and MEK6 toward their substrates p38 MAP kinase and JNK/SAPK. TAO kinases play an essential role in signaling from physiological agonists to stress-responsive MAPK pathways. Autophosphorylation of TAO may contribute to its activation mechanism, with Ser181 located within the MEK binding domain.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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