Thermo Fisher Scientific P-Selectin Polyclonal Antibody
Thermo Fisher Scientific의 P-Selectin Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 rabbit IgG 기반 항체로, Western blot과 ELISA에 사용됩니다. 액상 형태로 제공되며, 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/glycerol buffer에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 220–319 of human CD62P/P-selectin (NP_0029962) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805021 |
Product Specific Information
- Immunogen sequence: FSFNSQCSFH CTDGYQVNGP SKLECLASGI WTNKPPQCLA AQCPPLKIPE RGNMTCLHSA KAFQHQSSCS FSCEEGFALV GPEVVQCTAS GVWTAPAPVC
- Positive Samples: Mouse kidney
- Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type I transmembrane glycoprotein involved in the regulation of cell rolling. It is stored in Weibel-Palade bodies of endothelial cells and in α-granules of platelets, and rapidly translocates to the cell surface upon activation by thrombin, histamine, complement 5a, Ca²⁺ ionophores, or ADP.
P-selectin mediates interactions between activated endothelial cells or platelets and leukocytes. It plays a key role in leukocyte adhesion, inflammation, atherogenesis, and thrombosis. Clinically, P-selectin helps distinguish heparin-induced thrombocytopenia with or without thrombosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-88593_P-Selectin_CD62P_P16109-1_Rabbit.svg, PA5-88593_P-Selectin_CD62P_P16109-1_Rabbit_PDP.jpeg)
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