Thermo Fisher Scientific CD51 Polyclonal Antibody
Human ITGAV(CD51)에 특이적인 Rabbit Polyclonal Antibody로, IHC(Paraffin)에서 1:1,000~1:4,000 희석 범위로 사용 가능. 보존제가 없으며 장기 보관 시 -20°C에서 보관 권장. Integrin alpha V 관련 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the human ITGAV |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788027 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for human ITGAV.
Target Information
ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, which combine with multiple integrin beta chains to form different integrins.
Among the known associating beta chains (β1, β3, β5, β6, and β8; ITGB1, ITGB3, ITGB5, ITGB6, and ITGB8), each interacts with extracellular matrix ligands. The αVβ3 integrin, also known as the Vitronectin receptor (VNR), is one of the most studied. In addition to adhesion, many integrins facilitate signal transduction.
Integrin β3 is found along with the αIIb chain in platelets. Integrins participate in cell adhesion and cell-surface mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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