Thermo Fisher Scientific DYNLRB1 Polyclonal Antibody
DYNLRB1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 사용 가능하며, 인간·마우스·랫트 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DYNLRB1 (Accession Q9NP97), corresponding to amino acid residues I50–E96 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853141 |
Product Specific Information
Antibody detects endogenous levels of total DYNLRB1.
Target Information
The DYNLRB1 gene belongs to the roadblock dynein light chain family. The encoded cytoplasmic protein binds intermediate chain proteins, interacts with transforming growth factor-beta, and regulates actin-modulating proteins. Upregulation of this gene is associated with hepatocellular carcinoma, suggesting involvement in tumor progression. Alternative splicing yields multiple transcript variants, and pseudogenes are found on chromosomes 12 and 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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