Thermo Fisher Scientific RNF41 Polyclonal Antibody
RNF41 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트에 반응하며, Affinity chromatography로 정제됨. 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RNF41 (Accession Q9H4P4), corresponding to amino acid residues V141–E191 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853151 |
Product Specific Information
This antibody detects endogenous levels of total RNF41.
Target Information
The RING-type zinc finger motif is present in various viral and eukaryotic proteins, consisting of a conserved cysteine-rich domain capable of binding two zinc atoms. Proteins containing this domain are typically involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317-amino acid protein that includes one RING-type zinc finger and one SIAH-type zinc finger. It is expressed in testis, ovary, and prostate, functioning as an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 enzyme to target substrates for degradation. Nrdp1 specifically interacts with ErbB-3 and UBPY, targeting them for proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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