Thermo Fisher Scientific MSI2 Monoclonal Antibody (2C11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

Immunohistochemistry (IHC)

1:200-1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2C11

Immunogen

Purified recombinant fragment of human MSI2 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_11157843

Product Specific Information

MA5-15821 targets MSI2 in IHC and WB applications and shows reactivity with Human samples.

The MA5-15821 immunogen is purified recombinant fragment of human MSI2 expressed in E. Coli.

MA5-15821 detects MSI2 which has a predicted molecular weight of approximately 35kDa.

Target Information

Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.