Thermo Fisher Scientific AMPK alpha-1 Monoclonal Antibody (2B7)
AMPK alpha-1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 등 여러 종에 반응하며 비결합형 액상 형태로 제공. 연구용으로 세포 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B7 |
| Immunogen | Purified recombinant fragment of human PRKAA1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11152993 |
Product Specific Information
MA5-15815 targets PRKAA1 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human, Mouse, Non-human primate, and Rat samples.
The immunogen is a purified recombinant fragment of human PRKAA1 expressed in E. coli.
MA5-15815 detects PRKAA1, which has a predicted molecular weight of approximately 64 kDa.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, typically the γ-phosphate of ATP, onto an acceptor amino acid in a substrate protein.
Through this mechanism, protein kinases mediate most signal transduction processes in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With over 500 gene products, the protein kinase family is one of the largest in eukaryotes, classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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