Thermo Fisher Scientific Phospho-CSK (Ser364) Polyclonal Antibody
Phospho-CSK (Ser364) 폴리클로날 항체로, 인간·마우스·랫트 시료에서 CSK 단백질의 인산화 상태 분석에 적합합니다. Western blot, IHC, ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | 1:100–1:300 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Csk around the phosphorylation site of S364 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608815 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
CSK is a tyrosine kinase that downregulates SRC oncoprotein activity through phosphorylation of its carboxy terminus. The CSK gene may function as an antioncogene and plays a role in regulating cell growth, differentiation, migration, and immune responses.
CSK phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1. It is expressed ubiquitously as a ~50 kDa cytosolic protein, with a fraction associated with lipid rafts via PAG (Csk-binding protein).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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