Thermo Fisher Scientific SPINK7 Polyclonal Antibody
SPINK7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 인체 및 마우스 반응성, Protein A 정제, 고농도(1 mg/mL) 액상 형태로 안정적 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SPINK7, amino acids 51–85 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein containing one Kazal-like domain. SPINK7 is thought to act as a serine protease inhibitor.
The SPINK7 gene maps to human chromosome 5, which contains approximately 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with several genetic conditions including Cockayne syndrome (ERCC8 gene), familial adenomatous polyposis (APC gene), and Treacher Collins syndrome (TCOF1 gene).
Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, and deletions of 5q or the entire chromosome 5 are common in therapy-related acute myelogenous leukemia and myelodysplastic syndrome.
Probable serine protease inhibitor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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