Thermo Fisher Scientific Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Rabbit Monoclonal Antibody (TOP1MT, 2883R)
인간 TOP1MT 단백질을 표적으로 하는 재조합 토끼 단일클론 항체. IHC(P) 실험에 최적화되어 있으며 HEK293 세포 발현 시스템에서 생산됨. 단백질 A/G로 정제된 액상 형태로 제공되며, 보존제 무첨가 PBS 버퍼에 저장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Topoisomerase I, Mitochondrial (TOP1MT) Recombinant Rabbit Monoclonal Antibody (TOP1MT, 2883R)
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TOP1MT, 2883R |
| Immunogen | Recombinant full-length human TOP1MT protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 min.
Target Information
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology.
The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription.
Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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