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Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/4451R)
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Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/4451R)

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PD-L1(CD274) 표적의 재조합 토끼 단클론 항체로, 암 면역치료 연구에 적합합니다. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능하며, Human 및 Mouse 반응성을 가집니다. Protein A/G 정제, 1 mg/mL 농도의 액상 형태로 제공됩니다.

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Thermo Fisher Scientific 29126RBM11P1ABX PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/4451R)

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA)) 1–2 µg/mL
Immunocytochemistry (ICC/IF) 1–2 µg/mL
Flow Cytometry (Flow) 1–2 µg/10⁶ cells

Product Specifications

Specification Description
Species Reactivity Human, Mouse
Host / Isotype Rabbit / IgG
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone PDL1/4451R
Immunogen Recombinant fragment (around aa 39–191) of human CD274 (PD-L1) protein
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A/G
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions –20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice

Target Information

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. Its receptor, programmed death receptor 1 (PD-1), negatively regulates T-cell receptor (TCR) signaling. Upon PD-L1–PD-1 interaction, TCR-mediated proliferation and cytokine production decrease. PD-L1 is abundantly expressed on many murine and human cancers and can be upregulated upon IFN-γ stimulation, suggesting its role in tumor immune evasion.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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