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Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/4451R)
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PD-L1(CD274) 표적의 재조합 토끼 단클론 항체로, 암 면역치료 연구에 적합합니다. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능하며, Human 및 Mouse 반응성을 가집니다. Protein A/G 정제, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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- 29126RBM11P1ABX
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- pk
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마지막 업데이트 2025. 08. 04. 오후 10:52
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Thermo Fisher Scientific 29126RBM11P1ABX PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL pk판매 단위 pk ·
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1,063,800원VAT 포함 1,170,180원
Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/4451R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PDL1/4451R |
| Immunogen | Recombinant fragment (around aa 39–191) of human CD274 (PD-L1) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. Its receptor, programmed death receptor 1 (PD-1), negatively regulates T-cell receptor (TCR) signaling. Upon PD-L1–PD-1 interaction, TCR-mediated proliferation and cytokine production decrease. PD-L1 is abundantly expressed on many murine and human cancers and can be upregulated upon IFN-γ stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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