Thermo Fisher Scientific NPHP3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human NPHP3(Accession Q7Z494), corresponding to amino acid residues T1111-A1161. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NPHP3,uniProtId:Q7Z494-1,ncbiNodeId:9606,antigenRange:1111-1161,antigenLength:1330,antigenImageFileName:PA5-100293_NPHP3_Q7Z494-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100293_NPHP3_Q7Z494-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2849807

Product Specific Information

Antibody detects endogenous levels of total NPHP3.

Target Information

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.