Thermo Fisher Scientific HSD17B8 Monoclonal Antibody (OTI2E12), TrueMAB
HSD17B8 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 IHC(P) 검증됨. 인간 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 57–261 of human HSD17B8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol and very low activity towards testosterone.
The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity and may play a role in mitochondrial fatty acid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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