Thermo Fisher Scientific RAB23 Polyclonal Antibody
RAB23 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 인간·마우스·개·랫에서 반응성이 예측됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PNKQRTKKNRNP) corresponding to the C-terminus amino acids of RAB23 (aa 219–226) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11000745 |
Product Specific Information
- Predicted to react with canine, human, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec, and Rho/Rab subfamilies. Rab proteins play key roles in endocytosis and biosynthetic protein transport, mediating the movement of carrier vesicles from the endoplasmic reticulum to the Golgi complex and secretory vesicles.
Rab23 (HSPC137) is a 237-amino-acid member of the Rab family, localized to the cytoplasmic side of the cell membrane. It is involved in intracellular protein transportation and signal transduction mediated by small GTPases. Mutations in the RAB23 gene may cause Carpenter syndrome (ACPS2), characterized by obesity, cardiac defects, polysyndactyly, and craniosynostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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