Thermo Fisher Scientific NF-H Polyclonal Antibody
Rabbit polyclonal antibody recognizing NF-H (Neurofilament heavy polypeptide). Validated for WB, IHC(P), and ICC/IF. Reacts with human, mouse, and rat. Supplied as a liquid, 1 mg/mL, affinity purified, in PBS with glycerol. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NEFH (Accession P12036), corresponding to amino acid residues M1–A40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900278 |
Product Specific Information
Antibody detects endogenous levels of total Neurofilament heavy polypeptide.
Target Information
Neurofilament heavy polypeptide (NF-H) is one of the major intermediate filament proteins found specifically in neurons. It plays a key role in maintaining neuronal caliber and axonal integrity. NF-H expression is tissue-specific and developmentally regulated, and it is implicated in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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