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Thermo Fisher Scientific PHLDA1 Polyclonal Antibody
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Thermo Fisher Scientific PHLDA1 Polyclonal Antibody

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Human PHLDA1 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 40% 글리세롤과 0.02% sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.

판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 08:58
Thermo Fisher Scientific PA584598 PHLDA1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
740,000원VAT 포함 814,000원

Thermo Fisher Scientific · Thermo Fisher Scientific PHLDA1 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

  • Tested Dilution: 0.25–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human PHLDA1 (Control fragment: RP-107243)
Conjugate Unconjugated
Form Liquid
Concentration 0.1 mg/mL
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions Wet ice
RRID AB_2791749

Product Specific Information

Immunogen sequence:
KGKYMYFTVV MAEGKEIDFR CPQDQGWNAE ITLQMVQYKN RQAILAVKST RQKQQHLVQQ QP


Target Information

Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity is a key effector mechanism in immunosurveillance against virus-infected or transformed cells. Two mechanisms account for this activity: the perforin-based process and the FAS-based mechanism involving FAS (APO-1) and its ligand (FAS-L).
Human FAS (APO-1) is a 48 kDa cell surface glycoprotein belonging to the receptor family that includes CD40, nerve growth factor receptors, and tumor necrosis factor receptors. FAS antigen is broadly expressed on lymphoid cell lines and is highly expressed in T cells following TCR crosslinking.
A previously undescribed protein, TDAG51, restores activation-induced apoptosis in cells lacking Fas expression in response to activation.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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