Thermo Fisher Scientific B7-H3 Polyclonal Antibody
B7-H3/CD276 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 적용 가능. Western blot 및 ELISA에 사용 가능하며 높은 특이성과 재현성을 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- View 1 publication
ELISA
- Tested Dilution: 1:20,000
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from the internal region of human CD276 (B7-H3), amino acids 130–157 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2636546 |
Product Specific Information
B7-H3 / CD276 Polyclonal Antibody detects endogenous levels of B7-H3 / CD276 protein.
Target Information
CD276, also known as B7-H3, is a member of the B7 family of co-stimulatory molecules.
It is a type I transmembrane protein that:
- Induces proliferation of CD4+ and CD8+ T cells
- Enhances generation of cytotoxic T cells
- Stimulates production of interferon gamma
Expression can be induced on dendritic cells and monocytes by inflammatory cytokines and is widely expressed in peripheral tissues such as heart, kidney, testis, and colon.
In humans, CD276 exists as two isoforms resulting from gene duplication and differential splicing.
It has therapeutic potential in regulating cell-mediated immune responses to cancer, particularly with anti-angiogenic therapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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