Thermo Fisher Scientific NOR-1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NOR-1 (NR4A3) for IHC applications. Reacts with multiple species including human, dog, and bat. High specificity via antigen affinity purification. Supplied as liquid form, 1 mg/mL in PBS with sodium azide. Fo...
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Thermo Fisher Scientific NOR-1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Dog, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from near C-terminus of human NR4A3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551373 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- 100%: Human, Gorilla, Gibbon, Monkey, Dog, Bat, Elephant, Panda
- 95%: Marmoset, Rat, Bovine, Hamster, Rabbit, Pig
- 90%: Mouse
Target Information
NOR-1 (NR4A3) is a NR4 nerve growth factor-like receptor involved in neuronal development, T-cell apoptosis, and cancer progression. It binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 expression is rapidly and transiently induced by various stimuli. Downregulation of NOR-1 and other NGFI-B family members correlates with drug addiction-prone behavior in Lewis rats.
Three human isoforms are known: NOR-1, NOR-1β, and NOR-1 3′ variant.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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