Thermo Fisher Scientific EDAR Polyclonal Antibody
Human EDAR 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보존됩니다. 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Western Blot (WB): 1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EDAR. Recombinant protein control fragment (Product #RP-90259) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.06 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640881 |
Product Specific Information
Immunogen sequence:
TKDEDYGCVP CPAEKFSKGG YQICRRHKDC EGFFRATVLT PGDMENDAEC GPCLPGYYML ENRPRNIYGM VCYSCLLAPP NTKECVGATS GASANFPGTS
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 95%
Target Information
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein acts as a receptor for the soluble ligand ectodysplasin A and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is essential for the development of hair, teeth, and other ectodermal derivatives.
Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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