Thermo Fisher Scientific IMPDH2 Polyclonal Antibody
IMPDH2 단백질을 인식하는 Thermo Fisher의 염소 유래 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 합성 펩타이드 면역원 사용, 0.5 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
- 카탈로그번호
- PA519039
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- pk
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Applications and Tested Dilution
- Western Blot (WB): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KEEEHDCFLEEI) corresponding to the internal amino acids of IMPDH2 (aa 167–179) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980226 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 8,000.
Target Information
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis pathway. It is involved in maintaining cellular guanine deoxy- and ribonucleotide pools necessary for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is subsequently converted into guanosine-5'-monophosphate. Up-regulation of this gene has been observed in certain neoplasms, suggesting a potential role in malignant transformation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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