Thermo Fisher Scientific Human Neurotrypsin Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 23 amino acids near the amino terminus of human Neurotrypsin.
PEP-0483 can be used as a blocking peptide with polyclonal antibody PA5-20363.

Target Information

Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures involved in processing and storage of learned behavior and memory, such as the cerebral cortex, hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.