Thermo Fisher Scientific Phospho-SynGAP (Ser836) Polyclonal Antibody
SynGAP 단백질의 Ser836 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. 고순도 액상 형태로 제공되며 -20°C에서 안정적으로 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-SynGAP (Ser836) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human SynGAP around the phosphorylation site of Ser836 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Synaptic Ras-GTPase activating protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain. It is a major component of the postsynaptic density and associates with PSD-95 and NMDA receptors. SynGAP Ras-GTPase activity is inhibited by phosphorylation by CaM kinase II, suggesting its role as a negative regulator of MAP kinase activation in the absence of active NMDA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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