Thermo Fisher Scientific TNFRSF4 Monoclonal Antibody (UMAB277), UltraMAB
Human TNFRSF4(OX40/CD134) 단백질을 인식하는 mouse monoclonal antibody(UMAB277). IHC, ChIP, Peptide Array에 사용 가능. Lyophilized 형태, 1 mg/mL 농도. 연구용으로 면역학 및 암 면역치료 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ChIP assay (ChIP) | Assay-Dependent |
| Peptide Array (Array) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB277 |
| Immunogen | Full length human recombinant protein of human TNFRSF4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
OX40 (also known as CD134 or TNFRSF4) is a receptor expressed on the surface of activated T cells. It plays a key role in T cell proliferation, survival, and immune response enhancement.
Activation of OX40 strengthens immune responses against cancer and infections. OX40 agonists are being investigated as potential immunotherapies that may enhance the efficacy of chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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