Thermo Fisher Scientific TYMP Monoclonal Antibody (UMAB98), UltraMAB
TYMP 단백질을 인식하는 UMAB98 클론의 마우스 단일클론 항체. Western blot 및 IHC(파라핀 절편)에서 검증됨. 고순도의 액상 형태로 제공되며, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB98 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
A platelet-derived endothelial growth factor (PD-ECGF), also known as thymidine phosphorylase (TP) or gliostatin.
In the presence of inorganic orthophosphate, it catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate.
It is chemotactic and mitogenic for endothelial cells and acts as a non-heparin binding angiogenic factor present in platelets.
Additionally, it is involved in the conversion of fluoropyrimidines—cytotoxic agents used in cancer therapy—into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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