Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI4B2), TrueMAB
TTLL12 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 사용 가능. Human 및 Rat 반응성. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. 암 연구 및 TTLL12 기능 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B2 |
| Immunogen | Full length human recombinant protein of human TTLL12 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TTLL12 (Tubulin Tyrosine Ligase-Like Family, Member 12) is a 644 amino acid protein containing one TTL domain.
Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized.
It is highly expressed in metastatic prostate cancer cell lines and considered a potential tumor therapy target.
Overexpression of TTLL12 may alter chromosome ploidy, while downregulation affects post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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