Thermo Fisher Scientific P2Y12 Polyclonal Antibody
Rabbit에서 유래한 P2Y12 폴리클로날 항체로, 인간 P2Y12 단백질(아미노산 1–45)에 대한 합성 펩타이드로 면역화됨. Western blot에 1:500–1:3,000 희석도로 사용 가능. 혈소판 응집 관련 연구 및 GPCR 기능 분석에 적합. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of Human P2Y12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546216 |
Product Specific Information
- Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
P2Y12 belongs to the family of G-protein coupled receptors. This family includes several receptor subtypes with overlapping pharmacological selectivity for various adenosine and uridine nucleotides.
This receptor is involved in platelet aggregation and represents a potential target for the treatment of thromboembolisms and other clotting disorders.
Two transcript variants encoding the same isoform have been identified for this gene. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions.
ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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