Thermo Fisher Scientific GPR32 Polyclonal Antibody
Thermo Fisher Scientific의 GPR32 Polyclonal Antibody는 인간 GPR32 단백질을 타겟으로 하는 항체로, WB, IHC, ICC/IF, Flow, Functional Assay에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| Functional Assay | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of Human GPR32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546212 |
Product Specific Information
- Recommended positive controls: H1299
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600–1,000 members and represents the largest known class of molecular targets with proven therapeutic value.
The intronless GPR32 gene encodes an orphan G protein-coupled receptor that binds to resolvin D1 and lipoxin A4.
Resolvin D1 binding to GPR32 has been linked to:
- Resolution of pulmonary inflammation
- Suppression of TGFβ-induced epithelial mesenchymal transition in A549 lung cancer cells
Resolvins are being evaluated as new drug candidates acting at the resolution phase of chronic inflammation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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